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Adenosine-sensitive right ventricular tachycardia in children
1Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara.
The Turkish Journal of Pediatrics
|January 1, 1997
Summary
Adenosine effectively terminates pediatric right ventricular outflow tachycardia. Verapamil provides favorable long-term arrhythmia suppression in children with this condition.
Area of Science:
- Pediatric Cardiology
- Electrophysiology
- Pharmacology
Background:
- Right ventricular outflow tachycardia (RVOT) is a specific type of idiopathic ventricular tachycardia (VT).
- RVOT presents unique clinical and electrophysiologic characteristics in pediatric patients.
Purpose of the Study:
- To evaluate the efficacy of adenosine in terminating idiopathic RVOT in children.
- To assess the long-term effectiveness of verapamil for managing this arrhythmia.
Main Methods:
- Patients underwent standard diagnostic tests (ECG, echocardiogram, etc.).
- Adenosine was administered intravenously to determine effective termination dose (max 300 µg/kg).
- Adenosine-sensitive patients received oral verapamil for long-term treatment.
Main Results:
- Adenosine successfully terminated VT in all seven pediatric patients studied.
- The mean effective adenosine dose was 183 ± 75 µg/kg.
- Verapamil treatment showed favorable long-term outcomes over a mean follow-up of 17 months.
Conclusions:
- Adenosine is an effective agent for acute termination of pediatric RVOT.
- Verapamil is a suitable and effective option for long-term management of RVOT in children.