Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Risk and risk management connected with xenograft].

J Julvez1, P Vannier

  • 1Unit¿e s¿ecurit¿e des greffes, ¿etablissement fran"cais des greffes, Paris, France.

Pathologie-Biologie
|June 27, 2000
PubMed
Summary

Animal viruses can transmit to humans, but pathogenicity is not inevitable. Strict preventive measures and surveillance are crucial for xenotransplantation safety to mitigate unquantifiable risks.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Emergence of a highly pathogenic variant of porcine reproductive and respiratory syndrome virus in Asia].

Virologie (Montrouge, France)·2022
Same author

Maternal iron status in early pregnancy and DNA methylation in offspring: an epigenome-wide meta-analysis.

Clinical epigenetics·2022
Same author

Mineralization and Preservation of an extremotolerant Bacterium Isolated from an Early Mars Analog Environment.

Scientific reports·2017
Same author

Science-based management of livestock welfare in intensive systems: looking to the future.

Revue scientifique et technique (International Office of Epizootics)·2014
Same author

A conceptual framework in the study of neuropsychological development in epidemiological studies.

Neuroepidemiology·2012
Same author

Early life environment, neurodevelopment and the interrelation with atopy.

Environmental research·2010

Area of Science:

  • Zoonotic disease transmission
  • Viral pathogenicity
  • Xenotransplantation safety

Context:

  • Animal viruses can transmit to humans, posing potential health risks.
  • While some viral transmissions are asymptomatic, others like influenza A cause significant mortality.
  • Limited outbreaks of hemorrhagic fevers and monkeypox gain media attention.

Purpose:

  • To evaluate the risks associated with animal virus transmission to humans, particularly in xenotransplantation.
  • To emphasize the importance of the precautionary principle in managing unquantifiable risks.
  • To outline comprehensive preventive and surveillance strategies for xenotransplantation.

Summary:

  • Human infections with simian viruses have been accidental and asymptomatic; monkeypox and endogenous retroviruses have not shown significant transmission.
  • The precautionary principle mandates proactive risk reduction at every stage of xenotransplantation.
  • Recommended measures include strict isolation, germ-free transport, rigorous surgical conditions, and extensive patient, family, and healthcare worker surveillance.

Impact:

  • Implementing rigorous safety protocols can minimize the risk of zoonotic disease transmission during xenotransplantation.
  • Long-term patient and contact surveillance, along with a national register, is vital for monitoring and managing potential incidents.
  • Ensuring the safety of xenotransplantation procedures protects recipients, their contacts, and public health.

Related Experiment Videos