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Cerebral activation during multiplication: a functional MR imaging study of number processing.

R K Fulbright¹, D L Molfese, A A Stevens

¹Department of Diagnostic Radiology, Yale University, New Haven, CT 06520-8042, USA.

AJNR. American Journal of Neuroradiology

|June 28, 2000

Summary

This study used functional MRI (fMRI) to investigate brain activity during multiplication. Results show that multiplication and number memory share brain networks, with the left frontal lobe playing a key role.

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Area of Science:

Neuroscience
Cognitive Neuroscience
Neuroimaging

Background:

Number processing is thought to involve interconnected neuronal networks.
Understanding the neural basis of mathematical operations like multiplication is crucial.

Purpose of the Study:

To elucidate the specific brain regions engaged during multiplication using functional magnetic resonance imaging (fMRI).
To compare brain activation patterns between multiplication, matching, and control tasks.

Main Methods:

Eighteen adults underwent fMRI while performing matching, multiplication, and control tasks.
Participants judged stimuli based on presented numbers; responses were recorded.
Statistical parametric mapping analyzed brain activation differences between tasks.

Main Results:

Both matching and multiplication tasks activated regions including the medial superior frontal gyrus, anterior cingulate, and intraparietal sulci.
Left frontal lobe regions showed prolonged activation during multiplication compared to matching.
Differential activation patterns were observed in the middle frontal gyrus between tasks.

Conclusions:

Multiplication and number memory share an integrated network of brain regions.
The left frontal lobe, crucial for memory and language, is significantly involved in multiplication.