Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cryptococcal osteomyelitis of the spine.

S Govender1, E Mutasa, A H Parbhoo

  • 1Department of Orthopaedic Surgery, University of Natal, Durban, South Africa.

The Journal of Bone and Joint Surgery. British Volume
|June 29, 2000
PubMed
Summary

Cryptococcal spondylitis, a fungal infection of the spine, can cause neurological deficits. Early tissue diagnosis is crucial for effective treatment and recovery, especially in endemic areas.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The mysterious joint: Septic arthritis and acute osteomyelitis due to Fusarium species in a child with type II Chiari malformation.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2026
Same author

Prehospital emergency response and management of pregnancy-associated haemorrhage in KwaZulu-Natal Province, South Africa: A Retrospective Cross-Sectional Study.

African journal of emergency medicine : Revue africaine de la medecine d'urgence·2026
Same author

An open letter: In solidarity with all children suffering in wars; to all who hold or share a concern for the wellbeing of children.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2025
Same author

Response: Why solidarity with all children suffering in wars is not antisemitic.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2025
Same author

Knowledge, attitude and practice of emergency care providers on obstetric haemorrhage in KwaZulu-Natal, South Africa: A cross-sectional study.

African journal of emergency medicine : Revue africaine de la medecine d'urgence·2025
Same author

The academic progress of female general surgery and orthopaedic surgery trainees in South Africa.

South African journal of surgery. Suid-Afrikaanse tydskrif vir chirurgie·2024

Area of Science:

  • Infectious Diseases
  • Neurology
  • Neurosurgery

Background:

  • Cryptococcal spondylitis is a rare but serious spinal infection.
  • Neurological deficits are common presentations.
  • Spinal tuberculosis is a frequent mimic in endemic regions.

Purpose of the Study:

  • To report on the treatment and outcomes of cryptococcal spondylitis.
  • To highlight the diagnostic challenges and importance of tissue biopsy.

Main Methods:

  • Retrospective case series of seven patients with cryptococcal spondylitis.
  • Treatment regimens included Amphotericin-B with 5-flucytosine or ketoconazole.
  • Clinical and neurological outcomes were assessed.

Main Results:

  • Five patients presented with neurological deficits; one was HIV-positive.
  • Three patients achieved complete neurological recovery with treatment.
  • Fungal infection mimicked spinal tuberculosis.

Conclusions:

  • Cryptococcal spondylitis requires prompt diagnosis and treatment.
  • Tissue diagnosis is essential to differentiate from spinal tuberculosis.
  • Antifungal therapy can lead to neurological recovery.

Related Experiment Videos