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[Cryopreservation. State of the art]
1Sezione di Patologia Riproduttiva, Istituto Clinico Humanitas, Rozzano MI. paolo.levi_setti@humanitas.it
Summary
Cryopreservation of embryos and oocytes aids fertility treatments by managing excess embryos from in vitro fertilization. This review explores current cryopreservation techniques and future developments in assisted reproduction.
Area of Science:
- Reproductive biology
- Cryobiology
- Assisted reproductive technology
Context:
- Increasing stimulation cycles per patient in in vitro fertilization (IVF) and embryo transfer procedures.
- Accumulation of excess embryos necessitates storage for subsequent transfer cycles.
- Ethical and legal considerations surrounding embryo storage.
Purpose:
- To review the current state of cryopreservation for human embryos and oocytes.
- To discuss the evolution of cryopreservation techniques since 1984.
- To explore potential future advancements in cryopreservation technology for fertility preservation.
Summary:
- Cryopreservation was developed to manage excess embryos from IVF, enabling later transfer and reducing multiple pregnancies.
- Technological advancements have made embryo and oocyte cryopreservation a standard practice in many fertility centers.
- The review covers the historical context, current methodologies, and future prospects of cryopreservation in reproductive medicine.
Impact:
- Facilitates efficient use of embryos in assisted reproduction, potentially improving success rates.
- Addresses the challenges of multiple pregnancies and reduces the need for repeated ovarian stimulation.
- Provides a foundation for understanding the current landscape and future directions in fertility preservation techniques.