Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Congenital malformations in Shimla.

N Grover1

  • 1Department of Pediatrics, Indira Gandhi Medical College, Shimla.

Indian Journal of Pediatrics
|July 6, 2000
PubMed
Summary

Congenital malformations occurred in 1.78% of 10,100 births. Stillborn babies had a significantly higher incidence (15.1%) of birth defects compared to live births (1.3%).

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

ITPA polymorphisms do not predict additional risk beyond TPMT and NUDT15 for thiopurine-induced cytopenia in inflammatory bowel disease.

Revista de gastroenterologia de Mexico (English)·2023
Same author

Modeling of live-birth rates and cost-effectiveness of oocyte cryopreservation for cancer patients prior to high- and low-risk gonadotoxic chemotherapy.

Human reproduction (Oxford, England)·2017
Same author

Toxic Epidermal Necrolysis : A Case Report.

Medical journal, Armed Forces India·2016
Same author

Detection of TB antigen by rapid test kit.

Medical journal, Armed Forces India·2016
Same author

Heterogeneous vancomycin-intermediate among methicillin resistant Staphylococcus aureus.

Medical journal, Armed Forces India·2015
Same author

In vitro vancomycin susceptibility amongst methicillin resistant Staphylococcus aureus.

Medical journal, Armed Forces India·2014

Area of Science:

  • Medical Research
  • Pediatrics
  • Obstetrics

Background:

  • Congenital malformations represent a significant global health concern, impacting infant mortality and morbidity.
  • Understanding the incidence and patterns of these defects is crucial for public health initiatives and clinical management.

Purpose of the Study:

  • To determine the incidence and types of congenital malformations in a tertiary care hospital setting.
  • To identify risk factors associated with congenital malformations, including stillbirths and maternal characteristics.

Main Methods:

  • A retrospective study analyzing 10,100 consecutive births (including stillbirths) over five years.
  • Data collection included birth outcomes, malformation types, maternal age, gravida, and birth weight.

Main Results:

  • Overall incidence of congenital malformations was 1.78%.
  • Stillborn babies exhibited a higher incidence (15.1%) compared to live births (1.3%).
  • Central nervous system defects were most common (40%), followed by musculoskeletal (23.8%). Higher incidence observed in mothers >35 years, gravida four+, and low birth weight babies (<2500g).

Conclusions:

  • Congenital malformations pose a significant risk, particularly in stillbirths.
  • Maternal age, high gravida, and low birth weight are associated risk factors.
  • Further research into specific malformation types and prevention strategies is warranted.

Related Experiment Videos