Related Experiment Video
Updated: Aug 2, 2026

Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model
Published on: April 3, 2016
[Strabismus and binocular vision disorders in premature infants with retinopathy treated with cryotherapy]
J Kobylarz1, A Kubatko-Zielińska, M Starzycka
1Katedry i Kliniki Okulistyki CM UJ w Krakowie.
Insights
Children treated for retinopathy of prematurity often develop vision problems. Cryotherapy for retinopathy of prematurity increases risks of refractive errors and strabismus, necessitating early childhood vision screenings.
Area of Science:
- Ophthalmology
- Pediatric Medicine
- Retinal Diseases
Context:
- Retinopathy of prematurity (ROP) is a significant cause of visual impairment in premature infants.
- Cryotherapy is a common treatment for active-phase ROP.
- Early detection and management of visual complications are crucial for long-term outcomes.
Purpose:
- To determine the prevalence of refractive errors, strabismus, and binocular vision disorders in children who underwent cryotherapy for ROP.
- To identify potential risk factors associated with these visual abnormalities.
Summary:
- A study of 67 children (aged 2-7) treated for ROP with cryotherapy found high rates of visual issues.
- Refractive errors affected 94% (hypermetropia 54%, myopia 40%), and strabismus was prevalent (52% esotropia).
- Normal binocular vision was present in only 54% of participants, with higher squint rates in lower birth weight groups.
Impact:
- ROP treated with cryotherapy is a significant risk factor for refractive errors, strabismus, and amblyopia.
- Routine vision assessments in early childhood are essential for infants with ROP.
- Findings highlight the need for comprehensive ophthalmological follow-up in this vulnerable pediatric population.
Purpose:
To assess frequency of refraction errors, abnormal eye position and binocular vision disorders in children with retinopathy treated with cryotherapy.
Material And Methods:
Subjects of the study were 67 children, aged 2-7, treated with cryotherapy for active phase retinopathy.
Results:
The largest group consisted of children with good visual acuity (48%). Refraction error was found in 94% of the examined eyes. Hypermetropia was more common (54%) than myopia (40%). Majority of the examined children had squint, and esotropia was much more frequent (52%). The deviation in 37% of children was over 10 degrees. In the group with birth weight under 1000 grams as well as in those with birth weight 1000-1500 grams the squint occurred in 48%, and in children weighing over 1500 grams in 4.0%. Only 54% of the studied children had normal binocular vision.
Conclusions:
Retinopathy of prematurity is a risk factor for development of refraction errors, strabismus and amblyopia. In infants with retinopathy of prematurity treated with cryotherapy it is necessary to have vision check-ups during their early childhood years.
More Related Videos
11:03Subretinal Transplantation of Human Embryonic Stem Cell Derived-retinal Pigment Epithelial Cells into a Large-eyed Model of Geographic Atrophy
Published on: January 22, 2018
11:20Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
Published on: June 14, 2021