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A clinical audit on the practice of platelet transfusions at a tertiary paediatric referral centre

R Jamal1, T S Hoe, L C Ong

  • 1Department of Paediatrics, Hospital Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia.

Insights

An audit found that 18.5% of platelet transfusions were inappropriate due to a lack of clear clinical practice guidelines. Developing detailed local guidelines is recommended to improve transfusion appropriateness and patient care.

Area of Science:

  • Hematology
  • Clinical Pathology
  • Quality Improvement in Healthcare

Background:

  • Platelet transfusions are vital for managing thrombocytopenia and other bleeding disorders.
  • Inconsistent clinical practice can lead to inappropriate platelet utilization.
  • Establishing clear guidelines is essential for quality transfusion medicine.

Purpose of the Study:

  • To audit the appropriateness of platelet transfusion indications at the Paediatric Institute, Kuala Lumpur Hospital.
  • To identify areas for improvement in platelet transfusion practices.
  • To assess the need for localized clinical practice guidelines.

Main Methods:

  • A prospective audit was conducted over one month.
  • Retrospective data from the preceding month were collected for comparison.
  • A predefined set of criteria, agreed upon by an audit committee, was used to evaluate transfusion appropriateness.

Main Results:

  • Out of 119 cases reviewed, 18.5% (22 cases) demonstrated inappropriate indications for platelet transfusion.
  • The audit highlighted variability in current transfusion practices.

Conclusions:

  • There is a significant incidence of inappropriate platelet transfusions.
  • A need exists for more detailed, locally relevant clinical practice guidelines.
  • Implementing specific guidelines can reduce inappropriate platelet transfusions and optimize resource use.

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