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Peritoneal coccidioidomycosis: case report and review
1Division of Infectious Diseases, St. Paul's Hospital, Vancouver, British Columbia V6Z 1Y6 Canada. pphils@hivmet.ubc.ca
Abstract:
Peritonitis is an unusual extrapulmonary manifestation of coccidioidomycosis. Peritoneal involvement often has an indolent course and may resolve spontaneously. Optimal management has not been defined; however, fluconazole's spectrum of activity, pharmacokinetic profile, and efficacy in dialysis-related yeast peritonitis suggest that it may be an effective treatment. To our knowledge, we report the first case of coccidioidal peritonitis treated with fluconazole and review the literature.
Insights
Coccidioidal peritonitis, a rare fungal infection, can resolve spontaneously. This study presents the first case treated with fluconazole, suggesting its potential efficacy for this extrapulmonary manifestation.
Area of Science:
- Infectious Diseases
- Mycology
- Nephrology
Background:
- Peritonitis is an uncommon extrapulmonary sign of coccidioidomycosis.
- Peritoneal involvement typically follows an indolent progression and may resolve without intervention.
Observation:
- This case report details the first instance of coccidioidal peritonitis successfully treated with fluconazole.
- The patient's condition was managed using fluconazole, a medication known for its antifungal properties.
Findings:
- Fluconazole's effectiveness in treating yeast peritonitis in dialysis patients suggests its potential utility in coccidioidal peritonitis.
- The study highlights the successful application of fluconazole in a patient with coccidioidal peritonitis.
Implications:
- This case suggests fluconazole as a potential therapeutic option for coccidioidal peritonitis.
- Further research is warranted to define optimal management strategies for this rare condition.