Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bone cells and matrices in orthopedic tissue engineering.

J E Fleming1, C N Cornell, G F Muschler

  • 1Department of Orthopaedic Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.

The Orthopedic Clinics of North America
|July 6, 2000
PubMed
Summary

Harnessing osteogenic cells and designing conductive scaffolds offers new solutions for skeletal tissue regeneration. This approach optimizes cell capacity for targeted repair, advancing clinical applications in skeletal reconstruction.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comparative Assessment of Primary Osteoarthritis Progression Using Conventional Histopathology, Polarized Light Microscopy, and Immunohistochemistry.

Cartilage·2020
Same author

Classification systems for platelet-rich plasma.

The bone & joint journal·2019
Same author

Donor-matched comparison of chondrogenic progenitors resident in human infrapatellar fat pad, synovium, and periosteum - implications for cartilage repair.

Connective tissue research·2019
Same author

Primary Cells Isolated from Human Knee Cartilage Reveal Decreased Prevalence of Progenitor Cells but Comparable Biological Potential During Osteoarthritic Disease Progression.

The Journal of bone and joint surgery. American volume·2018
Same author

Histopathological assessment of primary osteoarthritic knees in large patient cohort reveal the possibility of several potential patterns of osteoarthritis initiation.

Current research in translational medicine·2017
Same author

Evaluation of rhBMP-2/collagen/TCP-HA bone graft with and without bone marrow cells in the canine femoral multi defect model.

European cells & materials·2015

Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Cell Biology

Background:

  • Osteogenic cells possess inherent capacity for skeletal tissue regeneration.
  • Current limitations in skeletal repair necessitate innovative therapeutic strategies.
  • Engineered matrices can enhance cell function and guide tissue formation.

Purpose of the Study:

  • To explore the potential of osteogenic cells for targeted skeletal tissue repair.
  • To investigate the role of specialized matrices as conductive scaffolds.
  • To advance cell-matrix composite applications in skeletal reconstruction.

Main Methods:

  • Harvesting and manipulation of osteogenic cells.
  • Design and fabrication of specialized conductive scaffolds.

Related Experiment Videos

  • Development of cell-matrix composites for skeletal applications.

    • Main Results:

    • Demonstrated the feasibility of using osteogenic cells for targeted regeneration.
    • Showcased the efficacy of conductive scaffolds in supporting cell function.
    • Highlighted the potential of cell-matrix composites in addressing clinical challenges.

    Conclusions:

    • Optimizing the use of osteogenic cells and engineered matrices presents a promising avenue for skeletal tissue regeneration.
    • Engineered matrix materials and cell-matrix composites offer novel solutions for skeletal reconstruction.
    • This approach holds significant potential for improving clinical outcomes in treating skeletal defects.