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Gene therapy for spine fusion
S N Khan1, C Hidaka, H S Sandhu
1SpineCare Institute, Hospital for Special Surgery, New York, New York 10021, USA.
The Orthopedic Clinics of North America
|July 6, 2000
Abstract:
Gene therapy is a novel therapeutic modality for repair and regeneration of musculoskeletal tissues, including the spine. Various methods for therapeutic gene transfer are presented in this article. Several studies in which gene transfer has been used specifically to enhance spine fusion in animal models are reviewed.