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Updated: Aug 10, 2026

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications
Published on: August 4, 2018
In vitro activity of telithromycin (HMR 3647) and seven other antimicrobial agents against anaerobic bacteria
G Ackermann1, R Schaumann, B Pless
1Institute for Medical Microbiology and Epidemiology of Infectious Diseases, Liebigstrasse 24, University of Leipzig, Germany. ackermg@medizin.uni-leipzig.de
Abstract:
We assessed the in vitro activity of telithromycin (HMR 3647) and seven other antimicrobials against 292 strains of obligately anaerobic bacteria. MICs were determined with the microdilution technique and Wilkins-Chalgren broth according to DIN 58940-83. MIC50/MIC90s (mg/L) for telithromycin were 4/4 for Bacteroides fragilis, Bacteroides ovatus and Bacteroides thetaiotaomicron, 2/4 for Fusobacterium spp. and Bilophila wadsworthia, 2/2 for Bacteroides caccae, 1/4 for Bacteroides vulgatus, 0.25/4 for Prevotella spp., > or =0.03/0.5 for Clostridium spp. and 0.125/4 for Peptostreptococcus spp.
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