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[Insular system of animals in a chronic heparin deficiency]
1Laboratory of Protective Blood Systems, School of Biology, Moscow State University, Russia.
Abstract:
The chronic heparin deficiency achieved by long-term treatment (for 3 weeks) with protamine-sulfate is accompanied by the development of stable hyperglycemia, decreased glucose tolerance, and the appearance of insulin resistance. Administration of exogenous heparin promotes the restoration of normoglycemia.