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Spinal lipomatous malformations.

A Jindal1, A K Mahapatra

  • 1Department of Neurosurgery, All India Institute of Medical Sciences, New Delhi. ajindal@yahoo.com

Indian Journal of Pediatrics
|July 8, 2000
PubMed
Summary
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Spinal lipomatous malformations (SLM) are neural tube defects treated surgically. Surgery offers a 95% chance of neurological improvement or stabilization for patients with SLM.

Area of Science:

  • Neurosurgery
  • Developmental Biology
  • Pediatric Neurology

Background:

  • Spinal lipomatous malformations (SLM) encompass closed neural tube defects characterized by excessive lipomatous tissue in the spinal cord or filum terminale.
  • These malformations often present with cutaneous markers such as subcutaneous lipomas, hypertrichiosis, and dermal sinuses, alongside orthopedic issues like foot deformities and limb shortening.

Purpose of the Study:

  • To evaluate the clinical features, diagnostic methods, and surgical outcomes of spinal lipomatous malformations.
  • To determine the efficacy and risks associated with surgical management of SLM.

Main Methods:

  • Retrospective analysis of 65 patients with SLM treated surgically over seven years.
  • Diagnostic evaluation included MRI and CT myelography.

Related Experiment Videos

  • Surgical interventions addressed lipomas, tethering, and associated anomalies like Chiari malformations and hydrocephalus.

    • Main Results:

    • The majority of patients (56/65) presented with neurological deficits.
    • Surgical intervention resulted in improvement or stabilization of neurological status in approximately 95% of patients (61/65).
    • Postoperative complications included CSF leaks (8 cases) and wound infections (4 cases), with a 5% incidence of new neurological deficits.

    Conclusions:

    • Aggressive surgical management is recommended for all patients diagnosed with spinal lipomatous malformations.
    • Early surgical intervention can significantly improve neurological outcomes and minimize the risk of progressive deficits.