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Updated: Jul 19, 2026

In Vitro Model of Physiological and Pathological Blood Flow with Application to Investigations of Vascular Cell Remodeling
Published on: November 3, 2015
Paradoxical effects of viscosity on the VentrAssist rotary blood pump
S Vidakovic1, P Ayre, J Woodard
1VentrAssist P/L, Sydney, Australia.
Abstract:
The ability of the VentrAssist blood pump to perform at its optimum design point is determined by a number of factors such as geometry of the pump, surface roughness, and fluid properties. Once the fluid properties are known, the performance characteristics of the pump can be optimized for that fluid. It is important to understand the effects of dynamic viscosity mu (called simply viscosity hereafter) on the performance characteristics and stability of the pump. The performance envelope of the pump and the needs of the patient must be matched. The VentrAssist pump has no shaft, seals, or fixed bearings and relies on the fluid-dynamic forces to maintain its effective performance. A number of different fluids have been tested to determine the effects of viscosity and density on pump performance. These include aqueous glycerol, red blood cells (RBCs) suspended in phosphate buffered saline solution (PBS), and Haemaccel. The effects of viscosity on the bearing stiffness, stage efficiency, and the pressure-flow rate (HQ) are characterized. The experimental results show a slight increase in the pressure rise across the pump shown as a positive upward shift of the H-Q curves with a decrease in viscosity; however, this is relatively small. A paradox in system efficiency exists: for a given fluid asymptotic viscosity, the system efficiency (product of magnetic and stage efficiency) using Haemaccel or PBS is greater than for the same viscosity of aqueous glycerol.
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