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Published on: October 12, 2017
Paediatric urinary tract infection and the necessity of complete urological imaging
E J Kass1, K M Kernen, J M Carey
1Department of Urology, Paediatric Division, William Beaumont Hospital, Royal Oak, MI 48073, USA.
Insights
Voiding cysto-urethrography (VCUG) is crucial for diagnosing vesico-ureteric reflux (VUR) in children with urinary tract infections (UTI), even with normal ultrasounds and renal scans. Approximately 23% of children showed significant VUR in this study.
Area of Science:
- Pediatric Nephrology
- Diagnostic Imaging
- Urology
Background:
- Urinary tract infections (UTI) are common in children.
- Renal scarring and vesico-ureteric reflux (VUR) are significant concerns.
- Current guidelines recommend imaging to detect VUR.
Purpose of the Study:
- To assess the utility of voiding cysto-urethrography (VCUG) in children with UTI.
- To determine the prevalence of VUR when initial imaging is normal.
Main Methods:
- Retrospective review of 468 renal scintigrams in children with UTI.
- Analysis of renal/bladder ultrasonograms for children with normal renal scans.
- Evaluation of VCUG for VUR in children with normal ultrasonography and renal scans.
Main Results:
- 101 children had both normal renal scans and ultrasonograms.
- 23% of these children (23/101) demonstrated VUR on VCUG.
- 14 had bilateral VUR, and 13 had grade III or higher VUR.
Conclusions:
- A significant percentage of children with UTI may have VUR despite normal renal scans and ultrasonography.
- VCUG remains an essential diagnostic tool for evaluating VUR in pediatric UTI cases.
- Early detection and management of VUR are critical to prevent renal damage.
Objective:
To evaluate voiding cysto-urethrography (VCUG) in assessing children with urinary tract infection (UTI) when renal/bladder ultrasonography and renal scintigraphy show no abnormality.
Patients And Methods:
A total of 468 renal scintigrams taken in children for an indication of UTI between January 1996 and December 1998 were reviewed. The renal and bladder ultrasonograms of those children with a normal renal scan were then reviewed. Children with both normal renal scans and normal ultrasonography were then evaluated for the frequency and grade of vesico-ureteric reflux (VUR) on VCUG.
Results:
Of the 468 patients, 453 (97%) had complete imaging studies; 152 of the children evaluated had normal renal scans, of whom 101 had a normal renal ultrasonogram. Twenty-three (23%) children with both a normal renal scan and renal/bladder ultrasonogram showed VUR on VCUG, of whom 14 had bilateral VUR and 13 grade III or higher VUR.
Conclusion:
This study indicates that about 23% of patients may have significant VUR despite both a normal renal scan and ultrasonogram. Therefore, VCUG remains important in evaluating and managing children with UTI.
Related Concept Videos
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
Imaging Studies I: Kidney, Ureter, and Bladder Studies
Imaging Studies II: Ultrasonography
Imaging Studies III: Computed Tomography
Imaging Studies V: Intravenous Urography and Retrograde Pyelography
Imaging Studies VI: Voiding Cystourethrography and Cystography

