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[When and how to stop anxiolytic drugs]
1Service de psychiatrie et de psychologie médicale, Hôpital Saint-Antoine, Paris. philippe.nuss@St.ap-hop-paris.fr
La Revue Du Praticien
|July 11, 2000
Summary
Anxiolytic withdrawal requires integrating patient data, considering pharmacological and psychological factors. Proper initial prescription guidelines are crucial for successful benzodiazepine discontinuation.
Area of Science:
- Pharmacology
- Psychiatry
- Clinical Medicine
Context:
- Anxiolytic withdrawal is a common but complex therapeutic goal.
- Benzodiazepines are frequently over-prescribed, leading to dependence and tolerance issues.
- Patient personality and emotional environment significantly influence withdrawal outcomes.
Purpose:
- To outline the necessary considerations for successful anxiolytic withdrawal.
- To emphasize the importance of initial prescription guidelines in managing withdrawal.
- To highlight the interplay of clinical, pharmacological, and psychological factors.
Summary:
- Successful anxiolytic withdrawal necessitates a comprehensive approach, integrating patient's clinical history, prescribed disorder, and individual psychological and pharmacological profiles.
- Factors such as patient personality, emotional environment, and the initial prescription's duration and dosage are critical for managing withdrawal.
- The efficacy of antidepressants in anxiety disorders contributes to benzodiazepine over-prescription, underscoring the need for careful initial prescribing and withdrawal planning.
Impact:
- Informing clinical practice to optimize anxiolytic withdrawal protocols.
- Reducing the incidence of problematic benzodiazepine dependence and associated withdrawal complications.
- Promoting rational pharmacotherapy and patient-centered care in anxiety disorder management.