Related Experiment Videos
Three cases of pityriasis rubra pilaris successfully treated with cyclosporin A
K Usuki1, M Sekiyama, T Shimada
1Department of Dermatology, Kagoshima University Faculty of Medicine, Japan.
Dermatology (Basel, Switzerland)
|July 15, 2000
Abstract
Background:
Pityriasis rubra pilaris (PRP) is reported to respond poorly to cyclosporin A (CsA).
Objective:
We attempted to determine the efficacy of CsA in the treatment of classic adult-type PRP.
Methods:
Three patients with classic adult-type PRP were treated with 5 mg/kg/day CsA.
Results:
A sustained clinical response was achieved within 2-4 weeks of therapy. Relapses were noted when the CsA dose was decreased to 1.2 mg/kg/day.
Conclusion:
CsA should be considered in the treatment of classical adult-type PRP.