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Hypoplastic left heart syndrome.

J M Simpson

    Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology
    |July 15, 2000
    PubMed
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    Prenatal diagnosis of hypoplastic left heart syndrome (HLHS) allows informed parental decisions and improves outcomes for affected newborns. Early detection ensures optimal surgical preparation, though long-term prognosis remains uncertain.

    Area of Science:

    • Pediatric Cardiology
    • Fetal Medicine
    • Congenital Heart Disease

    Background:

    • Hypoplastic left heart syndrome (HLHS) is a severe congenital heart defect.
    • Accurate diagnosis is possible during fetal development.
    • Historically, HLHS had an invariably lethal outcome.

    Discussion:

    • Prenatal diagnosis empowers parents with choices regarding management: surgery, non-intervention, or termination.
    • Improved short-to-medium term survival rates are observed.
    • Babies diagnosed prenatally can be prepared for surgery, optimizing their condition at intervention.

    Key Insights:

    • Fetal diagnosis of HLHS is accurate and timely.
    • Informed parental choice is facilitated by prenatal detection.

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  • Enhanced preparation for neonatal surgery improves outcomes.
  • Outlook:

    • Long-term prognosis for HLHS remains largely unknown.
    • Continued improvements in survival are anticipated.
    • Genetic counseling and detailed fetal echocardiography are recommended for families with a history of HLHS to assess recurrence risk.