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Updated: Jul 22, 2026
07:02
An Assay for Quantifying Protein-RNA Binding in Bacteria
Published on: June 12, 2019
SRPrises in RNA-protein recognition
P B Rupert1, A R Ferré-D'amaré
1Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109-1024, USA.
Structure (London, England : 1993)
|July 15, 2000
Abstract:
The recent structure determination of the phylogenetically conserved cor re of the signal recognition particle (SRP) reveals a novel of highly un usual RNA-protein interface, where non-canonical base pairs play a centr al role. The structure shows how a helix-turn-helix motif can be employ ed to bind RNA and offers hints as to how the signal peptide is recogniz ed by the SRP.
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