Inhaled anesthetic binding sites in human serum albumin

R G Eckenhoff1, C E Petersen, C E Ha

  • 1Department of Anesthesia, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104-4283, USA. reckenho@mail.med.upenn.edu

Summary

Researchers discovered a new anesthetic binding site in human serum albumin (HSA) domain III, distinct from the previously known Trp-214 site. This finding reveals differential anesthetic selectivity and stabilization of HSA conformation.

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