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Published on: February 9, 2021
[Urinary calcium/creatinine excretion in children with isolated hematuria]
W Zoch-Zwierz1, T Porowski, A Wasilewska
1I Kliniki Chorób Dzieci AM w Białymstoku.
Insights
Children with hematuria showed higher oxalate and calcium excretion, though not significantly. Elevated levels were notable in those with kidney stones or abdominal pain, indicating potential links.
Area of Science:
- Pediatric Nephrology
- Clinical Chemistry
Context:
- Hematuria in children can indicate underlying renal issues.
- Oxalate and calcium levels are key indicators in kidney health.
Purpose:
- To evaluate oxalate and calcium excretion in children with hematuria.
- To compare excretion levels between children with and without hematuria.
Summary:
- Children with hematuria exhibited increased mean oxalate and calcium excretion compared to healthy controls.
- These differences were not statistically significant (p > 0.05).
- Significantly higher oxalate and calcium excretion was observed in children with renal stones and those with abdominal pain and family history.
Impact:
- Suggests a potential role for oxalate and calcium dysregulation in pediatric hematuria.
- Highlights the need for further investigation into metabolic factors in children with unexplained hematuria or abdominal pain.
Abstract:
The aim of this study was to assess the oxalate excretion (Ox) in 23 children aged 3-17 years with haematuria (I), using the enzymatic method. Control group (II) consisted of 21 healthy children. The results showed out that in children with haematuria both mean oxalate excretion (Ox/ker) and mean calcium excretion (Ca) and calcium/creatinine ratio (Ca/ker) were higher than in control group. However, the differences were not significant important (p > 0.05). Significantly higher oxalate and calcium excretion was diagnosed in 5 children with renal stone disease and 8 children without stones but with paroxysmal abdominal pain and positive family history.
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