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Biology and pathobiology of neuronal development
1Department of Neurology, Division of Neuroscience, Children's Hospital, Boston, Massachusetts 02115, USA. pomeroy@hub.tch.harvard.edu
Abstract:
Differentiation of neurons within the central nervous system occurs by the combined effects of intrinsic genetic programs and epigenetic stimuli. Disorders causing mental retardation and other abnormalities of higher cortical function arise by disturbances of the normal developmental sequence. MRDD Research Reviews 6:41-46, 2000.