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Marked prolongation of skin homograft survival with niridazole. A first report
Plastic and Reconstructive Surgery
|January 1, 1975
Abstract:
Niridazole, a nitroheterocyclic drug used to treat helminth infections is reported for the first time to suppress cell-mediated immunity, as ascertained by multiple in vivo assays. Skin homograft survival time was significantly prolonged in mice, without loss of animals due to drug toxicity.