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Guillain-Barré syndrome presenting with severe pain: report of one case.

P H Li1, H S Chang, H Y Huang

  • 1Department of Pediatrics, Mennonite Christian Hospital, Hualien, Taiwan.

Acta Paediatrica Taiwanica = Taiwan Er Ke Yi Xue Hui Za Zhi
|July 27, 2000
PubMed
Summary

Pediatric Guillain-Barré syndrome (GBS) can cause severe pain, often underestimated by clinicians. Prompt recognition and management of pain in pediatric GBS are crucial for recovery.

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Area of Science:

  • Neurology
  • Pediatrics
  • Immunology

Background:

  • Guillain-Barré syndrome (GBS) is an autoimmune disorder affecting the peripheral nervous system.
  • Pain is a common but often overlooked symptom in pediatric GBS.
  • Early diagnosis and intervention are critical for managing GBS complications.

Observation:

  • A 10-year-old girl presented with severe headache, lower extremity numbness, neck rigidity, and facial palsy.
  • She experienced intense pain in her neck, back, and calves, significantly impacting sleep.
  • Within 8 days, she developed tetraplegia and autonomic dysfunction, requiring mechanical ventilation.

Findings:

  • The patient received high-dose intravenous immunoglobulin (2 g/kg) over two days.
  • Gradual improvement was noted, though joint pain persisted for three weeks.

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  • Full recovery, including unaided walking and running, was achieved within six months.

    • Implications:

    • This case highlights the significant burden of pain in pediatric GBS.
    • It underscores the need for comprehensive pain assessment and management in children with GBS.
    • Effective treatment with IVIg can lead to substantial recovery, emphasizing the importance of timely intervention.