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Primary spinal germinoma in a patient with concomitant Klinefelter's syndrome
O Ganslandt1, M Buchfelder, G G Grabenbauer
1Department of Neurosurgery & Radiology, University of Erlangen-Nürnberg, Germany. ganslandt@neurochir.med.uni-erlangen.de
British Journal of Neurosurgery
|July 27, 2000
Abstract:
It is known that patients with Klinefelter's syndrome are inclined to develop concomitant malignant tumours, as well as extragonadal germ cell tumours. The association of a primary spinal germinoma in a patient with Klinefelter's syndrome is reported for the first time, and the coincidence of elevated gonadotropin levels and oncogenesis is discussed.