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Published on: February 17, 2023
Acute community-acquired diarrhea requiring hospital admission in Swiss children
B Essers1, A P Burnens, F M Lanfranchini
1Department of Pediatrics, University of Bern, Bern, Switzerland.
Insights
Common childhood diarrhea pathogens like Aeromonas, Cryptosporidium, and diarrheagenic E. coli were identified in over half of hospitalized children. This study highlights key infectious agents causing pediatric diarrheal illness.
Area of Science:
- Pediatric Infectious Diseases
- Microbiology
- Public Health
Background:
- Diarrheal illness is a significant cause of childhood morbidity worldwide.
- Identifying causative agents is crucial for effective treatment and prevention strategies.
Purpose of the Study:
- To determine the prevalence of various pathogens responsible for community-acquired diarrhea in hospitalized children.
- To identify the most common infectious agents contributing to pediatric diarrheal illness.
Main Methods:
- Stool specimens were collected from 312 consecutive children admitted with community-acquired diarrhea.
- Microbiological evaluation was performed to detect a range of bacterial, viral, and parasitic pathogens.
Main Results:
- Pathogens were detected in 166 (53%) of the 312 children studied.
- Rotavirus was the most common pathogen (n=75), followed by Salmonella spp. (n=37) and Campylobacter spp. (n=24).
- Aeromonas spp., Cryptosporidium, and various diarrheagenic Escherichia coli strains were also significant contributors.
Conclusions:
- A substantial proportion of pediatric diarrheal cases are linked to identifiable pathogens.
- Agents such as Aeromonas, Cryptosporidium, and diarrheagenic E. coli are important causes of childhood diarrhea requiring hospitalization.
Abstract:
In order to ascertain the prevalence of agents that cause childhood diarrheal illness, stool specimens of 312 consecutive children with community-acquired diarrhea requiring admission were evaluated. Pathogens were detected in 166 (53%) of the 312 children (>/=2 pathogens in 28 children): Rotavirus (n=75), Salmonella spp. (n=37), Campylobacter spp. (n=24), Shigella spp. (n=5), Giardia spp. (n=4), Yersinia spp. (n=2), Aeromonas spp. (n=15), Cryptosporidium (n=15), enteropathogenic Escherichia coli (n=13), enterotoxigenic E. coli (n=7), and enterohemorrhagic E. coli (n=5). In conclusion, acute childhood diarrheal illness pathogens, such as Aeromonas, Cryptosporidium, and diarrheagenic E. coli, account for a large proportion of patients with a microbiologically positive stool specimen.
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