[50 years of recurrence]

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Conservative Site-specific Recombination and Phase Variation02:53

Conservative Site-specific Recombination and Phase Variation

Because the DNA segments are cut and reorganized in a direction-specific manner, site-specific recombination has emerged as an efficient genetic engineering technique. Flippase and Cyclization recombinases or Flp and Cre, respectively, are two members of the tyrosine recombinase family derived from bacteriophages, that are used to mediate site-specific DNA insertions, deletions, and targeted expression of proteins in mammalian cell lines.
The recognition sites for Cre recombinase called LoxP...
Relative Frequency Histogram01:14

Relative Frequency Histogram

The relative frequency depicts the proportion of data points that have each value. The frequency tells the number of data points that have each value. Like the histogram, a relative frequency histogram also has the same shape with a horizontal scale (the x-axis), but the vertical scale (the y-axis) is marked with relative frequencies (percentages of the whole) instead of actual frequencies. A relative frequency histogram is a graphical representation of a frequency distribution where the...
Relative Frequency Distribution00:55

Relative Frequency Distribution

A relative frequency distribution is the proportion or fraction of times a value occurs in a data set. To find the relative frequencies, one can divide each frequency by the total number of data points in the sample. It is very similar to a regular frequency distribution, except that instead of reporting how many data values fall in a class, a relative frequency distribution reports the fraction of data values that fall in a class. These fractions or proportions are called relative frequencies...
Cumulative Frequency Distribution01:04

Cumulative Frequency Distribution

A cumulative frequency distribution is another type of frequency distribution. Instead of reporting how many data values fall in some classes, it reports how many data values are contained in either that class or any class to its left. Technically, it means the sum of frequencies of the class and all the classes below it in a frequency distribution. A cumulative frequency is calculated by adding the frequency of each class lower than the corresponding class interval or category. In general, a...
Crossing Over01:30

Crossing Over

Crossing over is the exchange of genetic information between homologous chromosomes during prophase I of meiosis I. Genetic recombination gives rise to allelic diversity in the newly formed daughter cells. In humans, crossing over produces genetically distinct haploid egg and sperm cells that undergo fertilization to produce unique offspring. Before cell division starts, the germ cell’s chromosome(s) undergo duplication in the S phase of the cell cycle. As the cells enter prophase I, duplicated...
Interval and Radius of Convergence01:29

Interval and Radius of Convergence

A power series is a mathematical representation of a function as an infinite sum of terms involving powers of a variable. Such series converge only for specific input values, making it essential to determine the range over which the series produces valid results. This leads to the concepts of radius and interval of convergence, which define where the series behaves meaningfully.The radius of convergence describes the distance from the center within which the power series converges. For a...