[Therapeutic algorithms in infectious ulcers of cornea]

Based on the experience gained at Department of Infections and Allergic Diseases of the Eyes and recent publications, the author proposes protocols of drug therapy of the major infectious ulcerative diseases of the cornea: herpetic ulcer, ulcer caused by Pseudomonas aeruginosa, gonococci, staphylococci, fungi, and acanthamedian keratitis. The authors emphasizes that the treatment of ulcers of the cornea should be complex, including specific therapy (corresponding to the identified agent or the agent most probable as judged from the clinical picture) and pathogenetic therapy (metabolic, antiallergic, antiinflammatory, immunomodulating, hypotensive). If corneal ulcer is rapidly recognized and forced therapy started, good results can be attained even in such a fulminant infection as those caused by Pseudomonas aeruginosa or gonococci. On the other hand, therapy of keratomycosis and acanthamebian keratitis remains a problem.