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[Clinical study on myxoma and chordoma in the skull base]
Objective:
The clinical manifestation, neuroimaging properties, and pathologic changes of myxoma and chordoma were studied.
Methods:
Their neuroimaging properties and pathologic changes of myxoma 7 cases and chordoma 13 cases were analyzed.
Results:
(1) Clinical manifestation: the injury of oculomotor nerve and exorbitism is dominant in myxoma, but the injury of posterior cranial nerves is dominant in chordomas. (2) Plain skull X-ray film: local irregular punctate calcification and osseous necrosis were common in myxoma. Clivus invasion moruloid calcification and cauliflower-like calcification are always seen in chordoma. (3) CT and MRI: Location of the tumor and their relations with the adjacent structure were clear. (4) Pathologic changes: Cells are punctately arranged in myxoma, and vesicularly arranged in chordoma.
Conclusion:
The clinical study of myxoma and chordoma is not only useful for their differiental diagnosis, but can provide valuable clues for their surgical approach as well.