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[Clinical analysis of postoperative radiotherapy for stage I endometrial cancer]
Objective:
To evaluate the role and complications of adjuvant radiotherapy for stage I endometrial cancer after surgery.
Methods:
From May, 1986 to December, 1995, 20 patients with stage I endometrial cancer received total abdominal hysterectomy with bilateral salpingo-oophorectomy(TAH/BSO), and additional pelvic lymph node dissection in 5 cases. Most of the patients received radio therapy in 2-4 weeks after surgery. The radiation fields included pelvic lymph nodes with a total dose of 40-50 Gy.
Results:
All the patients had survived for 10 years. Only one patient developed distant metastases. Acute radiation reaction was observed in all patients. Late radiation-induced damage occured in six patients and was severe in two.
Conclusion:
Postoperative radiotherapy in the management of stage I endometrial cancer is beneficial for the controal of local recurrence but has relatively high frequency of late radiation injury.