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Updated: Aug 19, 2026

Orthotopic Implantation and Peripheral Immune Cell Monitoring in the II-45 Syngeneic Rat Mesothelioma Model
Published on: October 2, 2015
[Clinical analysis of 19 patients with pleural mesothelioma]
Objective:
To summarize the experience in the diagnosis of pleural mesothelioma.
Methods:
Analysing the clinical data of 19 patients with pleural mesothelioma, including age, history of exposure to asbestos, clinical manifestations, imaging and laboratory examinations and metastases.
Results:
None of the 19 patients had history of exposure to asbestos. Eight cases(42.1%) had no obvious thoracodynia, 9 cases(47.4%) had pleural effusion limited to the right chest, and in 2 cases(10.5%) the brachialis plexus was involved, and in 1 case (5.3%) malignant mesothelial cells were detected in the pleural effusion. Pleural thickening or nodules were found in 13 cases on CT and in 9 cases by B ultrasonographic examination.
Conclusion:
Exposure to asbestos is not the only cause of pleural mesothelioma. Chest pain is not always associated with pleural mesothelioma. CT and B ultrasonography are of good help in the diagnosis of pleural mesothelioma.
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