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Updated: Aug 9, 2026

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An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
Published on: April 17, 2013
[Anaplastic thyroid carcinoma with lung metastasis producing CA 19-9 and GM-CSF]
S Hoshi1, A Yoshizawa, H Arioka
1Department of Pulmonary Medicine, International Medical Center of Japan.
Summary
This case report details anaplastic thyroid carcinoma with lung metastasis. The tumor produced elevated CA 19-9 and granulocyte-macrophage colony-stimulating factor (GM-CSF), impacting patient prognosis.
Area of Science:
- Oncology
- Endocrinology
- Pathology
Background:
- Anaplastic thyroid carcinoma (ATC) is an aggressive endocrine malignancy.
- Metastatic spread significantly worsens the prognosis of thyroid cancers.
- Elevated tumor markers can indicate advanced disease and guide treatment.

