Cavitary pulmonary cryptococcosis complicated by aspergilloma

A roentgenogram of a 31-year-old office worker who had developed pleuritic pain showed multiple abscess cavities in the left lower lobe, and a clinical diagnosis of cryptococcosis was considered because of cryptococci recovered from a sputum smear and a positive indirect fluorescent antibody test. Lobectomy (after unsuccessful amphotericin therapy) proved the presence of a destructive cryptococcosis with Aspergillus proliferating in the cavities.