Related Experiment Videos
[Capillary hyperpermeability syndrome of the face]
E Andrès1, S Vinzio, A Ruellan
1Service de Médecine interne et Nutrition, Hôpitaux Universitaires de Strasbourg. Hautepierre@Wanadoo.fr
Presse Medicale (Paris, France : 1983)
|August 3, 2000
Summary
Capillary leak syndrome can manifest as facial edema and may be a paraneoplastic syndrome. Corticosteroids show promise in managing cancer-related capillary leak syndrome.
Area of Science:
- Internal Medicine
- Oncology
- Immunology
Background:
- Capillary leak syndrome (CLS) is a rare disorder characterized by recurrent episodes of diffuse edema.
- CLS presents with diverse clinical manifestations, posing diagnostic challenges.
Observation:
- A case of an 83-year-old woman with facial edema due to capillary leak syndrome is presented.
- The patient had follicular non-Hodgkin's lymphoma and elevated plasma interleukin-2 (IL-2) and interleukin-6 (IL-6) levels.
Findings:
- Facial edema can be a presenting symptom of capillary leak syndrome.
- CLS may be associated with paraneoplastic syndromes, particularly in the context of hematologic malignancies.
- Elevated levels of IL-2 and IL-6 were observed in this patient.
Implications:
- This case highlights the potential of capillary leak syndrome to present as facial edema.
- It suggests a paraneoplastic etiology for CLS in some instances.
- Corticosteroids may be beneficial in managing neoplasm-induced capillary leak syndrome.