Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Commissioning an image-guided localization system for radiotherapy.

M H Phillips1, K Singer, E Miller

  • 1University of Washington Medical Center, Department of Radiation Oncology, Seattle, WA 98195-6043, USA. mark@radonc.washington.edu

International Journal of Radiation Oncology, Biology, Physics
|August 5, 2000
PubMed
Summary

A new image-guided system offers accurate and precise patient positioning for cranial tumor radiotherapy, improving safety and efficiency. This system is robust in error detection and requires minimal extra setup time for clinicians.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Acellular pertussis vaccine given by accelerated schedule: response of preterm infants.

Archives of disease in childhood. Fetal and neonatal edition·2004
Same author

Anencephaly-something missing from the archaeological record?

Paleopathology newsletter·2003
Same author

Sero-epidemiology of mumps in western Europe.

Epidemiology and infection·2003
Same author

Severe and unrecognised: pertussis in UK infants.

Archives of disease in childhood·2003
Same author

Measurement and interpretation of pneumococcal IgG levels for clinical management.

Clinical and experimental immunology·2003
Same author

Nutrient removal from wastewaters using high performance materials.

Water science and technology : a journal of the International Association on Water Pollution Research·2003

Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Image-Guided Therapy

Background:

  • Fractionated external-beam therapy requires precise tumor localization.
  • Image-guided techniques enhance accuracy in radiotherapy for cranial tumors.
  • Existing systems necessitate improvements in flexibility and ease of use.

Purpose of the Study:

  • To design and commission an image-guided system for highly accurate target localization in fractionated radiotherapy.
  • To adapt a stereotactic radiotherapy system for cranial tumor treatments, including stereotactic radiotherapy, conformal radiotherapy, and intensity-modulated radiation therapy.
  • To ensure flexibility in treatment planning software, accuracy in repeat localization, and efficiency in system use.

Main Methods:

  • Adapted a commercially available stereotactic radiotherapy system for clinical use.

Related Experiment Videos

  • Integrated a stereo pair of cameras in the linac vault to track fiducial markers on a patient's biteblock.
  • Modified the system to support both dedicated stereotactic and general 3D radiation therapy planning programs.
  • Conducted measurements of localization accuracy, dose delivery, and patient positioning using various jigs and devices.
  • Main Results:

    • Achieved target localization accuracy comparable to existing treatment planning systems.
    • Demonstrated patient positioning accuracy of 1.0 +/- 0.2 mm in the radiation field.
    • Reported calibration accuracy of 0.76 mm using room lasers and 0.73 mm with a floor-based radiosurgery system.
    • Reduced positioning errors associated with couch rotation.

    Conclusions:

    • The developed system provides acceptable accuracy and precision for its intended clinical applications in cranial radiotherapy.
    • The system is robust in identifying errors and requires only a minor increase in setup time and effort.
    • Future research will explore its application in treating head-and-neck cancers outside the cranial vault.