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Published on: December 23, 2014
Venous thrombosis related to peripherally inserted central catheters
1Department of Surgery, UC Davis Medical Center, Sacramento, California 95817, USA.
The incidence of venous thrombosis associated with peripherally inserted central catheters (PICCs) is low. Using the smallest possible catheter diameter can help reduce the risk of developing this complication.
Area of Science:
- Vascular Surgery
- Medical Devices
- Thrombosis Research
Background:
- Peripherally inserted central catheters (PICCs) are widely used for long-term venous access.
- Catheter-related thrombosis is a potential complication that can lead to significant morbidity.
Purpose of the Study:
- To identify risk factors associated with venous thrombosis in patients who have PICCs.
- To evaluate the relationship between various factors and the development of PICC-related thrombosis.
Main Methods:
- A retrospective review of 813 PICCs placed in 678 patients between January and December 1997.
- Cross-referencing medical records with 1,631 venous duplex examinations performed during the same period.
- Analysis of factors including diagnosis, infusate, catheter tip position, vein accessed, and catheter diameter.
Main Results:
- The overall rate of PICC-associated venous thrombosis was 3.9%.
- Catheter diameter was the only statistically significant factor identified in multivariate analysis.
- No thromboses occurred with catheters ≤3 French (F); rates increased with larger diameters: 1% for 4-F, 6.6% for 5-F, and 9.8% for 6-F.
Conclusions:
- The incidence of venous thrombosis related to PICCs is low.
- Selecting the smallest appropriate catheter diameter is crucial for minimizing the risk of thrombosis.
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