Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Risks for developing critical illness with GI hemorrhage.

N Inayet1, Y Amoateng-Adjepong, A Upadya

  • 1Pulmonary and Critical Care Division, Bridgeport Hospital and Yale University School of Medicine, Bridgeport, CT 06610, USA.

Chest
|August 11, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Gastrointestinal Symptoms in Marfan Syndrome and Hypermobile Ehlers-Danlos Syndrome.

Gastroenterology research and practice·2018
Same author

Parenteral nutrition.

The journal of the Royal College of Physicians of Edinburgh·2015
Same author

Reforming Medicare--toward a modified Ryan plan.

The New England journal of medicine·2011
Same author

Endobronchial pseudo-tumour caused by herpes simplex.

The European respiratory journal·2005
Same author

Predictors of extubation outcome in patients who have successfully completed a spontaneous breathing trial.

Chest·2001
Same author

Gallstone pancreatitis: a community teaching hospital experience.

Journal of clinical gastroenterology·2001
Same journal

Wearable-derived activity and physiological changes following pleural intervention in malignant pleural effusion.

Chest·2026
Same journal

The effect of a two-day stay at high altitude (2500 m) on right ventricular afterload and oxygen delivery in patients with pulmonary vascular disease A randomized controlled crossover trial.

Chest·2026
Same journal

A Comparative Study of Radiation Exposure in Conventional and Robotic Bronchoscopy.

Chest·2026
Same journal

Independent Prognostic Contributions of Anti-Ro52 and Anti-MDA5 in Autoimmune-Associated Interstitial Lung Disease.

Chest·2026
Same journal

Lung aeration and gas exchange in SGA or AGA infants with moderate-severe BPD: secondary analysis of the PATH-BPD study.

Chest·2026
Same journal

Lung Cancer Incidence and Mortality after Negative Low-Dose CT Screening Results.

Chest·2026
See all related articles

Early identification of critical illness risk factors in gastrointestinal hemorrhage (GIH) is crucial. Hypotension, coagulopathy, neurologic changes, and high APACHE II scores predict subsequent instability.

Area of Science:

  • Critical care medicine
  • Gastroenterology
  • Internal medicine

Background:

  • Gastrointestinal hemorrhage (GIH) is a common cause of hospital admission.
  • Predicting which patients with GIH will develop critical illness is essential for appropriate resource allocation and patient management.

Purpose of the Study:

  • To identify risk factors present on initial hospital presentation that predict the subsequent development of critical illness in patients with GIH.
  • To evaluate the accuracy of these predictors in identifying patients who meet intensive care unit (ICU) admission criteria.

Main Methods:

  • An observational cohort study was conducted in a medical intensive care unit (ICU).
  • Demographic and physiological data were collected from 193 patients admitted with GIH.
  • Logistic regression analysis was used to identify independent predictors of meeting ICU admission criteria within the first 2 hours of presentation.

Related Experiment Videos

Main Results:

  • Thirty-four patients met ICU admission criteria within the initial 2 hours.
  • Admission prothrombin time (international normalized ratio > 1.2), hypotension (systolic BP < 90 mm Hg), acute neurologic changes, and an initial APACHE II score (>= 15) were the strongest predictors.
  • The presence of one or more of these factors had 88% sensitivity and 74% specificity for predicting subsequent critical instability.

Conclusions:

  • Coagulopathy, hypotension, neurologic dysfunction, and a high APACHE II score are key predictors of critical illness in GIH patients.
  • Many patients are admitted to the ICU without meeting local criteria, potentially leading to longer hospital stays.
  • Early identification of these risk factors can improve patient triage and resource utilization in critical care settings.