Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Adsorption in hemodialysis.

J Botella1, P M Ghezzi, C Sanz-Moreno

  • 1Department of Nephrology, Puerta de Hierro University Hospital, Madrid, Spain. jbotella@es.parkardbell.org

Kidney International. Supplement
|August 11, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sprint interval exercise disrupts mitochondrial ultrastructure driving a unique mitochondrial stress response and remodelling in men.

Nature communications·2025
Same author

Guardian of mitochondrial function: an expanded role of Parkin in skeletal muscle.

The Journal of physiology·2018
Same author

Mutual exclusivity and exclusion: Converging evidence from two contrasting traditions.

The Analysis of verbal behavior·2012
Same author

Psychological linguistics: A natural science approach to the study of language interactions.

The Analysis of verbal behavior·2012
Same author

A self-capitalization model for building behavior analysis graduate programs.

The Behavior analyst·2012
Same author

[Management of severe accidental hypothermia].

Medicina intensiva·2012
Same journal

Effect of kidney disease on glucose handling (including genetic defects).

Kidney international. Supplement·2011
Same journal

Need for better diabetes treatment for improved renal outcome.

Kidney international. Supplement·2011
Same journal

Glucose dynamics and mechanistic implications of SGLT2 inhibitors in animals and humans.

Kidney international. Supplement·2011
Same journal

SGLT2 inhibitors: molecular design and potential differences in effect.

Kidney international. Supplement·2011
Same journal

Glucose handling by the kidney.

Kidney international. Supplement·2011
Same journal

Bone: from a reservoir of minerals to a regulator of energy metabolism.

Kidney international. Supplement·2011
See all related articles

Sorbents like charcoal are being revisited for blood purification, regenerating ultrafiltrate into safe replacement fluid for hemodiafiltration and improving patient outcomes.

Area of Science:

  • Nephrology
  • Biomaterials Science
  • Chemical Engineering

Background:

  • Sorbents, including charcoal and resins, are crucial in blood purification techniques.
  • Early hemoperfusion with sorbents had adverse events, leading to decreased use.
  • Recent advancements have renewed interest in sorbent applications in combination therapies.

Purpose of the Study:

  • To review the evolving role of sorbents in blood purification.
  • To highlight the regeneration of ultrafiltrate using sorbents in hemodiafiltration.
  • To explore potential improvements in biocompatibility through sorbent technology.

Main Methods:

  • Review of sorbent classifications based on adsorption mechanisms (hydrophobic vs. chemical affinity).
  • Examination of historical and current applications of sorbents in dialysis and related techniques.

Related Experiment Videos

  • Analysis of paired filtration dialysis-charcoal for ultrafiltrate regeneration.

    • Main Results:

    • Sorbents are categorized by hydrophobic properties (charcoal, resins) and chemical affinity (ion exchange, chemisorbents).
    • Coated charcoal reduced adverse events in hemoperfusion but presented challenges in water control and acid-base balance.
    • Paired filtration dialysis-charcoal effectively regenerates ultrafiltrate into safe replacement fluid, removing uremic toxins.

    Conclusions:

    • Sorbents are increasingly integrated with modern blood purification methods like hemodiafiltration.
    • Ultrafiltrate regeneration using charcoal offers a promising approach for creating physiological replacement fluid.
    • Ongoing research focuses on adsorbing inflammatory substances to enhance biocompatibility in sorbent-assisted therapies.