[Sulpiride and drug addiction]

The authors carried on their study as presented in Tunis Congress of Psychiatry and Neurology. The results of the administration of Sulpiride with drug-addicts are still difficult to evaluate, because none of the patients are hospitalized and there is no possibility to know the precise doses absorbed by the patients. An improvement is however obvious with patients who spontaneously come to ask for more. They generally present polytoxicomania and use haschisch, opium-derivatives, amphetamines and usually L.S.D. Two recent observations summarize the action of Sulpiride: 1. --A fit of acute depersonnalisation in a young lady was suppressed within eight days with the administration of 1 g p.o. of Sulpiride a day. Recovery without relapse. 2. --An old drug-addict would shoot himself i.v. with at least 1 g of Sulpiride whenever he wanted to stop his intoxication periods. He did not feel any "flash" but only could thus obtain a "soft" withdrawal without need syndrome. Neither dependence, nor serious side-effects were observed.