Related Experiment Video
Updated: Oct 13, 2026
00:06
In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
Published on: August 20, 2019
Tbx12, a novel T-box gene, is expressed during early stages of heart and retinal development
C T Carson1, E R Kinzler, B A Parr
1MCD Biology, University of Colorado, Boulder, CO 80309-0347, USA.
Mechanisms of Development
|August 15, 2000
Abstract:
T-box genes encode transcription factors that regulate many developmental processes. We have cloned a novel mouse T-box gene, Tbx12. Tbx12 is the vertebrate homologue of the Drosophila H15 gene and the Caenorhabditis elegans tbx-12 gene. Tbx12 is expressed in extraembryonic tissues such as the amnion and allantois. In the embryo, Tbx12 is strongly expressed in the neural retina and the heart.
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