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[Changes in selected biochemical parameters during a low-calorie reducing diet]
1Klinika gerontologická a metabolická, Fakultní nemocnice, Hradec Králové, Czech Republic.
Aim Of The Study:
Assessment of the effect of short term modified low calorie diet on body weight and body mass index (BMI). Assessment of the effect of modified low calorie diet on blood lipids and some biochemical parameters.
Methods:
Before and after diet: body weight, BMI, whole blood count, platelet count, serum cholesterol, triglycerides and HDL cholesterol, serum creatinine, uric acid, urea, bilirubin, AST, ALT, pH of urine and atherogenic index (CHOL-HDL/HDL).
Patients:
11 male, mean age 52 years and 19 female, mean age 53.3 years.
Therapy:
Modified diet 14 days, 3.3 MJ daily, vitamins and minerals.
Results:
No significant difference was observed in platelet count, serum creatinine, urea, bilirubin, AST, ALT, pH of urine, HDL cholesterol and atherogenic index before and after modified low calorie diet. Significant loss of body weight and decrease of BMI, cholesterol and triglycerides occurred after modified diet. Serum uric acid significantly increased after weight loss.
Conclusion:
The present result's shows that a drop of serum cholesterol and triglycerides follows a significant loss of body weight after modified diet. Our result's shows a significant increase of uric acid levels after weight loss. There was no effect of body weight loss on other biochemical parameters.