Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Decreasing hypocomplementemia and membranoproliferative glomerulonephritis in Japan.

K Iitaka1, T Saka, K Yagisawa

  • 1Yamato City Hospital, Japan. iitaka@wd5.so-net.ne.jp

Pediatric Nephrology (Berlin, Germany)
|August 24, 2000
PubMed
Summary

Diagnoses of membranoproliferative glomerulonephritis (MPGN) and hypocomplementemia in Japanese children have decreased significantly since the 1980s. The reasons for this declining trend in MPGN and hypocomplementemia remain unknown.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

First Detection of Photons with Energy beyond 100 TeV from an Astrophysical Source.

Physical review letters·2019
Same author

Effect of Gender Differences on Transplant Kidney Function.

Transplantation proceedings·2017
Same author

Cryptococcal necrotizing fasciitis in a patient after renal transplantation--a case report.

Transplantation proceedings·2014
Same author

Reliability of a functional test battery evaluating functionality, proprioception, and strength in recreational athletes with functional ankle instability.

European journal of physical and rehabilitation medicine·2008
Same author

An autopsy case of pulmonary capillary hemangiomatosis without evidence of pulmonary hypertension.

Virchows Archiv : an international journal of pathology·2001
Same author

[Three cases of malignant lymphoma accompanied by renal cell carcinoma].

[Rinsho ketsueki] The Japanese journal of clinical hematology·2001

Area of Science:

  • Pediatric Nephrology
  • Immunology
  • Epidemiology

Background:

  • Membranoproliferative glomerulonephritis (MPGN) is a serious kidney disease.
  • Hypocomplementemia, a condition of low complement levels, is often associated with MPGN.
  • Understanding trends in MPGN and hypocomplementemia is crucial for public health initiatives.

Purpose of the Study:

  • To retrospectively investigate the incidence of childhood MPGN in an institution.
  • To analyze the trend of hypocomplementemia detected through school urinary screening in Japan.
  • To identify temporal changes in the occurrence of MPGN and hypocomplementemia.

Main Methods:

  • Retrospective analysis of MPGN diagnoses in children from 1974 to 1997.
  • Review of school urinary screening data for hypocomplementemia (low C3 levels) from 1980 to 1997.

Related Experiment Videos

  • Statistical comparison of incidence rates across different time periods.

    • Main Results:

    • A significant decreasing trend in MPGN diagnoses was observed from 1986 onwards compared to earlier periods.
    • The incidence of hypocomplementemia among schoolchildren with abnormal urinary findings also showed a significant decrease in later periods.
    • Both MPGN cases and hypocomplementemia incidence declined notably between 1974-1985 and 1986-1997.

    Conclusions:

    • Both new cases of MPGN and the incidence of hypocomplementemia are decreasing in Japan.
    • The underlying reasons for this observed downward trend in pediatric MPGN and hypocomplementemia are currently unknown.
    • Further research is needed to elucidate the factors contributing to this epidemiological shift.