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Published on: February 8, 2019
Age disorientation in schizophrenia: an indicator of progressive and severe psychopathology, not institutional
T C Manschreck1, B A Maher, L Winzig
1Department of Psychiatry and Psychology Laboratory for Clinical and Experimental Psychopathology, Harvard Medical School, Fall River, MA 02720, USA. Theo.Manschreck@dmh.state.ma.us
Abstract:
The authors investigated age disorientation in chronic schizophrenia to determine whether specific symptomatic, neurologic, and cognitive disturbances were linked to its presentation. Disorientation to their age was detected in 30% (16/54) of the schizophrenic patients in a chronic care facility. In matched comparisons, age-disoriented patients showed lower educational achievement, poorer mental state performance, and a greater severity of symptoms, as well as more severe motor and sensory impairments. Levels of social withdrawal did not differentiate the two groups. A two-hit model consistent with neurodevelopmental and neurodegenerative processes is proposed to explain the data.
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