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Related Experiment Videos

Osteolysis in cemented titanium alloy hip prosthesis.

E Schöll1, S Eggli, R Ganz

  • 1Department of Orthopaedic Surgery, University of Berne, Switzerland.

The Journal of Arthroplasty
|August 26, 2000
PubMed
Summary

Cemented titanium alloy hip stems (SLS-88) showed high rates of osteolysis and loosening, particularly smaller sizes. Researchers advise against their continued use due to bone degradation and implant failure risks.

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Area of Science:

  • Orthopedic Surgery
  • Biomaterials Science
  • Medical Device Engineering

Background:

  • Titanium alloy stems are commonly used in cemented hip arthroplasty.
  • Previous studies have not fully elucidated the long-term performance and failure modes of specific titanium alloy formulations like Ti6-Al7-Nb (SLS-88).

Purpose of the Study:

  • To evaluate the clinical and radiological outcomes of cemented Ti6-Al7-Nb (SLS-88) titanium alloy stems.
  • To identify factors contributing to osteolysis and loosening in these implants.
  • To assess the survivorship of these stems and provide recommendations for their use.

Main Methods:

  • Prospective evaluation of 132 consecutively implanted cemented Ti6-Al7-Nb (SLS-88) stems.
  • Mean follow-up of 6.6 years (range 5-7 years).

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  • Assessment of osteolysis, stem loosening (clinical and radiological), and pain patterns. Kaplan-Meier survivorship analysis was performed.

    • Main Results:

    • Nearly 30% of stems exhibited significant proximal osteolysis, correlating with a specific pain pattern.
    • Six stems required revision, and seven were clinically/radiologically loose, yielding 95% survivorship for revision and 88% for failure.
    • Smaller stem sizes were associated with increased osteolysis and loosening, linked to stem elasticity, micromotion, cement breakage, and corrosion.

    Conclusions:

    • Cemented Ti6-Al7-Nb (SLS-88) titanium alloy stems demonstrate a high incidence of osteolysis and loosening.
    • The combination of titanium's elasticity and corrosion accelerates bone-implant interface degradation, especially in smaller sizes.
    • The use of cemented SLS-88 titanium alloy stems is not recommended.