Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Conduction System of the Heart01:19

Conduction System of the Heart

11.8K
Autorhythmicity is a term that refers to the heart's inherent ability to generate electrical signals and instigate muscle contractions. This self-regulating conduction system within the heart consists of two key components: the pacemaker cells and specialized conducting cells.
The pacemaker cells are located in two primary nodes: the sinoatrial (SA) node and the atrioventricular (AV) node. The SA node pacemaker cells can autonomously depolarize, triggering an action potential that leads to the...
11.8K
Electrophysiology of Normal Cardiac Rhythm01:19

Electrophysiology of Normal Cardiac Rhythm

8.2K
The normal cardiac rhythm is a synchronized electrical activity that facilitates the regular and coordinated contraction of the heart muscle. This process is essential for efficient blood circulation throughout the body. The fundamental elements involved in establishing and maintaining this rhythm include the unique electrical properties of cardiac muscle cells, the sinoatrial (SA) node's pacemaker function, the specialized conducting system, and the ionic mechanisms underlying each phase...
8.2K
Propagation of Action Potentials01:23

Propagation of Action Potentials

8.1K
The propagation of an action potential refers to the process by which a nerve impulse, or "action potential," travels along a neuron.
Neurons (nerve cells) have a resting membrane potential, with a slightly negative charge inside compared to outside. This is maintained by ion channels, such as sodium (Na+) and potassium (K+) channels, which control the flow of ions. When a stimulus, like a touch or a signal from another neuron, triggers the neuron, sodium channels open, allowing sodium ions to...
8.1K
Mechanism of Cardiac Arrhythmias01:28

Mechanism of Cardiac Arrhythmias

1.4K
Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.
1.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sparsity-driven synchronization in oscillator networks.

Chaos (Woodbury, N.Y.)·2022
Same author

Unbalanced clustering and solitary states in coupled excitable systems.

Chaos (Woodbury, N.Y.)·2022
Same author

Edges of inter-layer synchronization in multilayer networks with time-switching links.

Chaos (Woodbury, N.Y.)·2021
Same author

Control of electron and electron-hole pair dynamics on nonlinear lattice bilayers by strong solitons.

Chaos (Woodbury, N.Y.)·2021
Same author

Shooting solitaries due to small-world connectivity in leaky integrate-and-fire networks.

Chaos (Woodbury, N.Y.)·2021
Same author

Generalized splay states in phase oscillator networks.

Chaos (Woodbury, N.Y.)·2021
Same journal

Exploring mechanisms for reversal of flow in tunicate hearts.

Chaos (Woodbury, N.Y.)·2026
Same journal

State estimation in spatiotemporal chaos via low-rank StatFEM.

Chaos (Woodbury, N.Y.)·2026
Same journal

Universal response functions in driven dissipative tunneling dynamics.

Chaos (Woodbury, N.Y.)·2026
Same journal

A network-based approach to characterize the dynamics of the coupling field of thermoacoustic oscillators in annular geometry.

Chaos (Woodbury, N.Y.)·2026
Same journal

Data-driven soliton manifold approximations for dark and bright waves: Some prototypical 1D case examples.

Chaos (Woodbury, N.Y.)·2026
Same journal

Gap junction architecture and synchronization clusters in the thalamic reticular nuclei.

Chaos (Woodbury, N.Y.)·2026
See all related articles

Related Experiment Video

Updated: Nov 27, 2025

Generation of Local CA1 γ Oscillations by Tetanic Stimulation
08:02

Generation of Local CA1 γ Oscillations by Tetanic Stimulation

Published on: August 14, 2015

9.4K

Structural anomalies in brain networks induce dynamical pacemaker effects.

I Koulierakis1, D A Verganelakis2, I Omelchenko3

  • 1Institute of Nanoscience and Nanotechnology, National Center for Scientific Research "Demokritos," 15341 Athens, Greece.

Chaos (Woodbury, N.Y.)
|December 2, 2020
PubMed
Summary
This summary is machine-generated.

Healthy brains exhibit complex chimera-like states, while tumorous brains show traveling waves originating from the tumor site. This research offers insights into brain dynamics and potential early tumor detection methods.

More Related Videos

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms
08:36

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms

Published on: March 21, 2019

7.5K
Acute In Vivo Electrophysiological Recordings of Local Field Potentials and Multi-unit Activity from the Hyperdirect Pathway in Anesthetized Rats
10:46

Acute In Vivo Electrophysiological Recordings of Local Field Potentials and Multi-unit Activity from the Hyperdirect Pathway in Anesthetized Rats

Published on: June 22, 2017

16.1K

Related Experiment Videos

Last Updated: Nov 27, 2025

Generation of Local CA1 γ Oscillations by Tetanic Stimulation
08:02

Generation of Local CA1 γ Oscillations by Tetanic Stimulation

Published on: August 14, 2015

9.4K
Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms
08:36

Dynamic Inter-subject Functional Connectivity Reveals Moment-to-Moment Brain Network Configurations Driven by Continuous or Communication Paradigms

Published on: March 21, 2019

7.5K
Acute In Vivo Electrophysiological Recordings of Local Field Potentials and Multi-unit Activity from the Hyperdirect Pathway in Anesthetized Rats
10:46

Acute In Vivo Electrophysiological Recordings of Local Field Potentials and Multi-unit Activity from the Hyperdirect Pathway in Anesthetized Rats

Published on: June 22, 2017

16.1K

Area of Science:

  • Computational Neuroscience
  • Network Science
  • Medical Imaging Analysis

Background:

  • Brain function relies on complex neuronal dynamics.
  • Tumors disrupt normal brain structure and function.
  • Understanding these dynamical changes is crucial for diagnosis and treatment.

Purpose of the Study:

  • To investigate the dynamical effects of tumors on brain networks.
  • To model brain activity using neuronal oscillators and MRI data.
  • To differentiate between healthy and tumor-affected brain dynamics.

Main Methods:

  • Numerical simulations of multilayer brain networks.
  • Utilizing neuronal oscillator models (FitzHugh-Nagumo, leaky integrate-and-fire).
  • Extracting network connectivities from Magnetic Resonance Imaging (MRI) data.

Main Results:

  • Healthy brains display chimera-like states with coherent and incoherent oscillatory regions.
  • Tumor-affected brains exhibit traveling waves initiated at the tumor site, acting as pacemakers.
  • Consistent findings across both neuronal models.

Conclusions:

  • Brain network dynamics differ significantly between healthy and tumor-affected states.
  • These findings could aid in early tumor detection before MRI visibility.
  • Provides a foundation for studying tumor evolution and impact.