Stationary phases for capillary electrochromatography
Related Experiment Video
Updated: Oct 13, 2026

Simple In-House Ultra-High Performance Capillary Column Manufacturing with the FlashPack Approach
Published on: December 4, 2021
1Analytical Chemistry Division, Chemical Science and Technology Laboratory, National Institute of Standards and Technology (NIST), Gaithersburg, MD 20899-8392, USA. mpursch@dow.com
Abstract:
This review summarizes the variety of stationary phases that have been employed for capillary electrochromatography (CEC) separations. Currently, about 70% of reported CEC research utilizes C18 stationary phases designed for liquid chromatography, but an increasing number of new materials (e.g., ion-exchange phases, sol-gel approaches, organic polymer continuous beds) are under development for use in CEC. Novel aspects of these different materials are discussed including the ability to promote electroosmotic flow, phase selectivity and activity for basic solutes. In addition, new column designs (polymer continuous beds and silica-sol-gel monoliths) are described.
Related Concept Videos
Capillary Electrophoresis: Applications
Capillary zone electrophoresis (CZE) separates ionic components based on their electrophoretic mobility. It has been used to separate proteins, amino acids,...
Capillary Electrophoresis: Instrumentation
Electrophoresis: Overview
There...
Gas Chromatography: Types of Columns and Stationary Phases
For an analyte to remain on the column for a sufficient amount of time, it must exhibit some level of compatibility (or...
Ion-Exchange Chromatography
Chromatography: Introduction
The phase in which the compounds linger or on which the compounds adsorb is called the stationary phase, whereas the mobile phase is the solvent that carries the solutes to be analyzed. In traditional column chromatography, the mixture flows through the stationary phase, and the compounds partition between the stationary and mobile phases...

