Improved column preparation and performance in capillary electrochromatography
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Updated: Oct 13, 2026

Curtain Flow Column: Optimization of Efficiency and Sensitivity
Published on: June 12, 2016
1Research Center of Nucleic Acid and Peptide Chemistry, Institut für Organische Chemie, Universität Tübingen, Germany.
Abstract:
Problems encountered in capillary electrochromatography, i.e. non-reproducible column manufacture, bubble formation during usage, short column lifetimes and limited choice of packing particles are addressed by the development of fritless or single-frit, internally tapered, segmented and dead-volume free coupled capillary columns. The Van Deemter plots measured demonstrate the performance of these high-quality capillaries which are suitable for capillary electrochromatography as well as for capillary high-performance liquid chromatographic applications.
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