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Sulfur-containing palladacycles: efficient phosphine-free catalyst precursors for the Suzuki cross-coupling reaction
1Laboratory of Molecular Catalysis, Instituto de Química, UFRGS, Av. Bento Gonçalves, 9500 Porto Alegre, RS 91501-970, Brazil.
Organic Letters
|August 31, 2000
Abstract:
[reaction: see text] Cyclopalladated compounds derived from the ortho-metalation of benzylic tert-butyl thioethers are excellent catalyst precursors for the Suzuki cross-coupling reaction of aryl bromides and chlorides with phenylboronic acid under mild reaction conditions. A broad range of substrates and functional groups are tolerated in this protocol, and highly catalytic activity is attained.