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Updated: Aug 8, 2026

Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report
Published on: February 12, 2018
Autologous conjunctival resurfacing of leaking filtering blebs
L D Harris1, G Yang, R M Feldman
1Hermann Eye Center, University of Texas Health Sciences Center at Houston, Houston, Texas, USA.
Purpose:
To present a case series of a new technique to repair late bleb leaks.
Design:
Retrospective, noncomparative, consecutive case series.
Participants:
Forty-seven autologous conjunctival resurfacings of late bleb leaks were performed by four surgeons at two institutions.
Methods:
Autologous conjunctival grafts were placed over existing de-epithelialized leaking blebs.
Main Outcome Measures:
Leak-free, Seidel-negative blebs and controlled glaucoma.
Results:
After a mean follow-up of 14 +/- 12 months, one patient continued to have bleb leak at the last follow-up, and one frank leak resolved with aqueous suppression. Intraocular pressure increased from 6.6 +/- 4.4 mmHg (0.13 glaucoma medications) to 11.9 +/- 4.1 mmHg (0.41 glaucoma medications).
Conclusions:
Conjunctival resurfacing with autologous tissue is an effective technique to repair late bleb leaks.

